Biomaterial

In the table below, entries in the left column refer to the related documentation, while the numbers in the cells of columns LASA-B to LASA-K refer to the corresponding LASA-data files (e.g. ‘850’ in column B refers to ‘LASAB850’). Table entries are hyperlinks. Hovering  over the waves in the header will show the years in which the corresponding measurements took place.

For more details about the LASA-waves, see Design LASA

LASA-WAVEBCDE2BFGH3BMBIJK
Cohort 1
Cohort 2
Cohort 3
Migrant Cohort
THEME BIOMATERIAL
Blood collection and overview
(routine) measurements

Response blood sampling /
DNA Date blood sampling
850


851		850


851		-


-		-


-		850


851		-


-		850


851		-


-
850


851		-


-

-


-
-


-		-


-
Routine measurements
(Albumin and cholesterol)
860860--860-860-860----
Adiponectin, leptin and ghrelin------879------
Apolipoprotein E (ApoE)
- Phenotyping
- Genotyping
870
-
-
-
-
-
-
-
-
870
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Cholesterol, triglycerides and
fructosamin
-867-----------
COLIA1 (Collagen type I α1 Sp1
polymorphism in LASA)
-871-----------
Cortisol (total plasma cortisol,
corticosteroid binding globuline,
salivary cortisol)
- Serum cortisol
- Salivary cortisol



-
-


864
-


-
-


-
880/
881/
882


-
-


-
-


-
-


-
-


-
-


-
-


-
-


-
-


-
-
Hair cortisol
(LASA ancillary study)
Genetic polymorphisms
(VDR, GR, etc)
- Vit D Receptors
- Haplotypes


-
-

872
873


-
-

-
-

-
-

-
-

-
-

-
-

-
-

-
-

-
-

-
-

-
-
GWAS data
-X--X-X-X----
Exome Chip
-X----X------
Homocysteine, vitamin B12, MMA
-866
-----------
Bone-related hormones and
bone turnover
-862
-----------
Inflammation factors
- Pro-inflammatory cytokine
Interleukin-6 (IL-6)
- Acute-phase proteins C-reactive
protein (CRP)
- A1-antichymotrypsin (ACT) 		861861------861----
Plasma and Serum Markers of
Alzheimer’s Disease and
endothelial dysfunction		-868----868

878
------
Serum 25-hydroxy-vitamin D
(25(OH)D) and parathyroid
hormone (PTH)
-862
--862-862-862----
Sex hormones
-863
-----------
Thyroid function
-865
-----------
Vitamin K status
----869--------
#
LASA-waveBCDE2BFGH3BMBIJK

† No blood drawn in wave E

‡ No sampling in waves D, F, H, MB (Migrant 1st cohort, Baseline), I, J and K